CNL Medical · Patient Education

Your Complete Guide to Qlosi Eye Drops for Presbyopia

Qlosi is an FDA-approved prescription eye drop that helps adults over 40 see clearly up close — no surgery, no reading glasses required. Here’s everything you need to know.

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Overview

What Are Qlosi Eye Drops?

Qlosi (pilocarpine hydrochloride 0.4%) is an FDA-approved prescription eye drop designed to treat presbyopia — the age-related loss of near vision that typically begins after 40. If you’ve started holding menus at arm’s length, squinting at your phone, or reaching for reading glasses more often, you know the feeling.

Qlosi offers a non-surgical, non-invasive alternative to reading glasses. One drop per eye, once or twice daily, and most patients notice clearer near vision within 20–30 minutes — lasting up to 8 hours.

CNL Medical’s board-certified providers can evaluate whether Qlosi is right for you and send a prescription to your pharmacy the same day — entirely online, no office visit needed.

Drug Facts

Drug NameQlosi (pilocarpine HCl)
Strength0.4% ophthalmic solution
Drug ClassCholinergic agonist
How TakenEye drop, once or twice daily
FormatSingle-use vials (preservative-free)
FDA ApprovedYes
Controlled SubstanceNo
Prescription RequiredYes
CNL Service StatesFL, NY, GA, AL

Mechanism

How Does Qlosi Work?

Qlosi works by gently constricting the pupil — creating what’s called a “pinhole effect.” Think of it like squinting to bring something into focus, but done precisely and comfortably by the drop itself.

This increased depth of focus allows nearby objects to appear sharper without altering the physical structure of your eye. Unlike surgery or corrective lenses, Qlosi works with your eye’s natural optics. The effects begin within 20–30 minutes of application and can last up to 8 hours.

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Apply One Drop

One drop per eye, once or twice daily as directed. Simple to fit into your morning routine.

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Pupil Constricts

Pilocarpine gently constricts the pupil, creating the pinhole effect that increases depth of focus.

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See Clearly

Within 20–30 minutes, near vision sharpens. Read, use your phone, and work at a screen with ease.

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Lasts Up to 8 Hours

Effects last up to 8 hours — enough to carry you through a full, productive day.

What to Expect

What Results Can You Expect?

Most patients with mild to moderate presbyopia experience meaningful improvement in near vision. Here’s what day-to-day life looks like on Qlosi:

✓ Reading books, menus, and labels without glasses
✓ Using your phone and tablet comfortably
✓ Working at a computer screen with less strain
✓ Less reliance on reading glasses throughout the day
✓ Effects kick in within 20–30 minutes of application
✓ Up to 8 hours of clearer near vision per dose

Individual Results Vary

Results depend on factors like pupil size, degree of presbyopia, and overall eye health. Your CNL Medical provider will help assess whether Qlosi is the right fit for your specific situation.

Side Effects

What to Know About Side Effects

Most side effects are mild and temporary, especially as your eyes adjust to the medication in the first few days.

Common Side Effects

Brief stinging when applied · Headache or brow ache · Temporary blurry vision · Difficulty seeing in low light · Temporary dim vision

Practical Tips

Apply in the morning · Remove contacts before use, reinsert after 10 min · Space other eye drops 5+ minutes apart · Avoid driving at night until you know your response

Contact a Provider If You Experience

Sudden flashes or new floaters · Shadow across your vision · Significant eye pain · Sudden vision loss · Redness, light sensitivity, or inflammation

At a Glance

Pros & Cons of Qlosi

Advantages

  • FDA-approved and clinically studied
  • Non-surgical and completely reversible
  • Preservative-free single-use vials — gentle on sensitive eyes
  • Flexible dosing — daily or as needed, up to twice per day
  • Works within 20–30 minutes
  • Available through convenient online prescription

Considerations

  • Requires a valid prescription
  • Effects wear off — not a permanent fix
  • May cause temporary low-light vision changes
  • Rare risk of retinal detachment
  • Not recommended with active eye inflammation (iritis)
  • CNL Medical service available in FL, NY, GA, and AL only

Getting Started

How to Get a Qlosi Prescription with CNL Medical

No waiting room. No appointment. Our board-certified providers can evaluate your eligibility and send a prescription to your pharmacy — all online, all on your schedule.

1

Sign Up on Push Health

Create a free account on the Push Health platform — HIPAA-compliant, secure, and takes just a few minutes.

2

Message Our Team

Request a Qlosi prescription or ask us any questions through the platform. No phone call required.

3

Receive Your Prescription

Once approved, your prescription is electronically sent to your local pharmacy or BlinkRx pharmacy for home delivery — same day in most cases.

States Where CNL Medical Can Prescribe Qlosi

CNL Medical is currently licensed to prescribe Qlosi in the following states. Visiting? You can still request a prescription during your stay.

🌴 Florida
🗽 New York
🍑 Georgia
⭐ Alabama

CNL Medical Consultation Fee
$60

Includes provider review and electronic prescription. Does not include the cost of medication at the pharmacy.

Medication Cost via BlinkRx
$79 / 30-day supply
$99 / 60-day supply

Fulfilled through BlinkRx with convenient home delivery. No hunting for it at a retail pharmacy.

Request Your Qlosi Prescription →

Common Questions

Frequently Asked Questions

A consultation with a licensed provider is legally required before receiving prescription medication. However, CNL Medical’s online service lets you complete that consultation by phone or secure message — no in-person visit needed. Our board-certified providers can write and electronically send your Qlosi prescription to BlinkRx pharmacy the same day.

Yes! If you are visiting Florida, New York, Georgia, or Alabama, you can create an account with CNL Medical through Push Health and request a Qlosi prescription. Once approved, it can be sent to BlinkRx for home delivery the same day.

CNL Medical charges $60 for the provider consultation and prescription. The medication itself is filled through our partner pharmacy BlinkRx — a 30-day supply is $79 and a 60-day supply is $99, with home delivery included.

CNL Medical typically responds within 1–2 hours. We ask patients to allow up to 12 hours in case of any delays. We are open 365 days a year from 9 AM to 9 PM.

Both Qlosi and Vizz are FDA-approved prescription eye drops for presbyopia, but they use different active ingredients. Qlosi contains pilocarpine 0.4% in preservative-free single-use vials. Vizz contains aceclidine and comes in a multi-dose bottle. Your CNL Medical provider can help determine which is better suited to your situation.

Both contain pilocarpine, but they differ in concentration and format. Qlosi is 0.4% pilocarpine in preservative-free single-use vials — gentler for sensitive eyes. Vuity is 1.25% pilocarpine in a multi-dose bottle with a preservative. Read our complete guide to Vuity, or your provider can walk you through which is the better fit.

Unopened foil pouches should be stored in the refrigerator. Once you open a pouch, the vials inside can be kept at room temperature (up to 77°F) for up to 30 days. Discard any unused vials after 30 days at room temperature.

Yes. CNL Medical operates through the Push Health platform, which is HIPAA-compliant and LegitScript certified. Payment is processed via Braintree, a leading web payment vendor, and credit card data is never stored in the system.

Safety

Important Safety Information

Please review the following before starting Qlosi. If any of these apply to you and you haven’t already told us, contact us before beginning treatment.

Night Vision

Because Qlosi constricts the pupil, it can reduce vision in low-light conditions. Use caution when driving at night or in poorly lit environments, especially in the first few days of use.

Retinal Conditions

Extra caution is advised for patients with a history of retinal detachment, prior serious eye injury, or previous eye surgery. A thorough medical screening is completed for every CNL Medical patient.

Eye Inflammation (Iritis)

Qlosi is not recommended for patients with active iritis. If you experience eye pain, redness, light sensitivity, or worsening blurry vision, stop use and contact us right away.

Contact Lens Use

Remove contact lenses before each use and wait at least 10 minutes before reinserting them. This helps the drop absorb properly and reduces irritation.

Single-Use Vials

Each vial is for one use only. Do not save opened vials — Qlosi is preservative-free, meaning bacteria can grow in a used vial. Discard after each application even if liquid remains.

Provider Oversight

Every CNL Medical patient completes a medical screening and provider review to help ensure that Qlosi is used safely and appropriately for their individual situation.

We’re Here for You

Ready to Try Qlosi?

Our team is available seven days a week, 9 AM to 9 PM. Get your prescription today — no appointment, no waiting room.

This page is for informational purposes only and does not constitute medical advice. Always follow the guidance of your CNL Medical provider regarding your specific treatment plan.

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